About

Andreas G. Weichert, PhD, has held international positions with increasing responsibility over the last 18 years. His expertise covers the entire spectrum of non-clinical drug R&D - from academic research on anti-tumor antibiotics at Stanford University to managing a discovery chemistry department in Big Pharma.

In his scientific assignments at AVENTIS and LILLY RESEARCH LABORATORIES he gained a broad understanding about all aspects of the pharmaceutical R&D value chain, contributing to and directing projects in all major therapeutic areas, with a focus on diabetes and cardiovascular indications.

Under his leadership, several research compounds were successfully advanced into the clinic. As a member of the international discovery management team at LILLY, he was also involved in diabetes project portfolio management and led the implementation of process innovations as well as outsourcing efforts.

Most recently, he founded Dr. WEICHERT - LIFE SCIENCES CONSULTING, recognizing the increasing demand for advice in translational research and process innovations in a complex and changing environment with minimized overheads.

Dr. Weichert received his PhD in Organic Chemistry from the University of Hanover, Germany. He is co-/author of more than 40 issued patents and 25 manuscripts.

Most recent research publications including a review article:

"Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site "Sheehan, S.M. et al., Bio. Med. Chem. Lett. 2007, 17, 1765.

"Allosteric activators of glucokinase: the development of cyclopropane-derived agents and their potential for use in the treatment of type two diabetes" Barrett, D.G. et al., 8th Intl. Symposium on adenosine and adenine nucleotides, Ferrara, Italy, May 24-28, 2006.

"Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators" Heuser, S. et al., Tet. Lett. 2006, 47, 2675.

Invited review:"Recent developments in the field of Na⁺/H⁺ inhibitors" Kleemann, H.-W. and Weichert, A.G., IDrugs 1999, 2(10), 1009-1025.